Progress Reports

Characteristics of mucosal glottic wave analyzed with HSDI- kymography, regional FFT, and red-color pattern after recurrent respiratory papillomatosis treated with laser surgery and intra-lesion bevacizumab injection

Raul M. Cruza,b , Krzysztof Izdebskia,b,c* (corresponding author) , Yuling Yanc

aOtolaryngology, Head & Neck Surgery, Kaiser Permanente Medical Center, Oakland, CA, USA

bPacific Voice and Speech Foundation, San Francisco, CA, USA

cBioengineering, Santa Clara University, Santa Clara, CA, USA

Visualizations by acoustics of voice stress: Is there an optical mucosal wave correlate?

Gra?yna Demenko a,b, Magdalena Jastrz?bskab,
Krzysztof Izdebskic,d, Yuling Yand

a Poznan Supercomputing and Networking Center, Poznan, (Poland)

b Department of Phonetics, A. Mickiewicz University of Poznan, Poznan, (Poland)

c Pacific Voice and Speech Foundation, San Francisco, CA (USA)

d Santa Clara University, Santa Clara (USA)

Does treatment of the laryngeal mucosa reduce dystonic symptoms? A prospective clinical cohort study of mannose binding lectin and other immunological parameters with diagnostic use of phonatory function studies

Mette Pedersen · Martin Eeg

This study examined eYcacy of the innate immune defence via the mannose binding lectin (MBL) in a cohort of 55 dystonic patients prospectively referred to the clinic with laryngeal mucosal complaints, who were placed on local steroids (budesonid inhaler, 400 !g 2 times daily) and antihistamines (fexofenadin 180 mg mostly 3 times daily) with adjuvant lifestyle corrections.

Gardasil® Immunization Effects on Laryngeal Papillomatosis: A Preliminary Study


The potential role of the adjuvant use of Gardasil® vaccine (series of three injections) in the treatment of recurring laryngeal papillomatosis (RRP) was evaluated in an adult population of 18 cases (12 m & 6 f, age range 37-79) being treated by one laryngologist with a long term meticulous CO2 laser removal every two-to-three months and than at double intervals, until no visible papillomas was observed by transoral magnified laryngovideostroboscopy (LVS), and when visual findings were questionable, verification was done by MDL with microscopic visualization. Thus each patient’s history was used as their control. Of the 18 cases, nine (5 m and 4 f) were still positive at the last in-the-office post final vaccination exam, while the remaining nine (7 m and 2 f) were negative for papilloma at the last post final vaccination office visit, within the range of eight to 27 months post final Gardasil® vaccine injection. This indicates a decrease in the recurrence (duration) time. The results also showed a reduction in papilloma clusters size and numbers found on recurrence by either LVS or by MDL.

Visual observations of glottic activity during didgeridoo performance

Krzysztof Izdebski, Lydia Hyde, Ronald R. Ward, Joel C. Ross, Pacific Voice and Speech Foundation, 3838 California Street # 505, San Francisco, CA 94118, USA

This paper was presented at the XX Annual Pacific Voice Conference

Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology

Conference Program Track: Photonic Therapeutics and Diagnostics Available in print as Proceedings of SPIE Volume 8207C

PVSF/SPIE held January 21, 2012 – 08:00 AM to January 23, 2012 – 6:00 PM at Moscone Center San Francisco, CA 94103